For some reason I'm unable to disable/uncheck anything in the enb gui whilst in game? For example I click to disable DOF but the tick just remains. I have to manually set it to false in the .ini file.

Any ideas?

Antivirus, skse plugin, some crapware hooking in to the game process and capture mouse and keyboard, win8 not properly configured by dpi setting (don't ask me about that, i just heard rumors).

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i5-4690k, 16Gb RAM, GTX 1060 6Gb, X-Fi Titanium, Win7 x128
I am INFP, not the brutal, godamnit.

I'm still on windows 7. I've since added the Skyrim Memory Patch to the skse.ini file by Sheson.

viewtopic.php?f=13&t=2729

Could this affect it?

No, it can't.

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i5-4690k, 16Gb RAM, GTX 1060 6Gb, X-Fi Titanium, Win7 x128
I am INFP, not the brutal, godamnit.

Anyone else? This guy doesn't seem to give a monkeys.

same problem here. im only able to change settings during the loading screens but as soon and those end I cant change any settings very frustrating.

Keys are hooked by some other software or skse plugin, what else should i say? It's your job to find what exactly cause this.

_________________
i5-4690k, 16Gb RAM, GTX 1060 6Gb, X-Fi Titanium, Win7 x128
I am INFP, not the brutal, godamnit.

ya im just asking sorry man. but nothing else is running and im not using skse so I have no idea what would be hooking the keys also. I can change the settings during the loading screen but not in the main menu or during game play its very weried.

Only win8 users reported such behavior because of something dpi related, skse users because of plugin for it, logitech tool. That's all i remember.

_________________
i5-4690k, 16Gb RAM, GTX 1060 6Gb, X-Fi Titanium, Win7 x128
I am INFP, not the brutal, godamnit.

Same issues here