The issue may mostly be dependent from enb preset to preset but does anyone know the precise cause of this?

I know for quite some time know it only ever happens to save games saved using the "ESC" key menu and clicking "SAVE" -> "New Save Game" aka "Manual Saving".

It does not happen to savegames made using the "save" command for instance; in the console menu or mods auto saving using that function.

First of all, which game?
For old skyrim when game is saved, one frame drawed to small resolution and mod ignore many processing code of it, but not objects processing (direct light, ambient, sky, particles, etc). So preview on saves looks different. Its basically mod bug, but i have no idea how to fix it at no costs.

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i5-4690k, 16Gb RAM, GTX 1060 6Gb, X-Fi Titanium, Win7 x128
I am INFP, not the brutal, godamnit.